High Shear Mixer Manufacturer | LHS Series

Working Principle

The High Shear Mixer can complete the processes of mixing, binder charging and granulating at one time, and by using impeller, the materials move axially, radially and tangentially in the container, so as to obtain the uniform mixed powder. The mixed powder is combined with binders or wetting agents to form soft materials, then the soft materials are formed as particles after cutting by chopper. Figure 1 shows the operation of high shear mixer. The features of particles prepared by wet granulation are: better surface modification, well-shaped appearance, strong wear resistance, good compression form-ability, etc.

High Shear Mixer is a machine of electricity and gas integrated equipment which applies PLC program control technology and frequency conversion control technology.The wet mixing granulator is an integrated machine, electricity and gas equipment that applies PLC program control technology and frequency conversion control technology. It is suitable for mixing and granulating powdery loose materials in the pharmaceutical, food, chemical and other industries, and can also be used for dry powder mixing.

Working Principle of the LHS Series High Shear Mixer

Technical Parameters

Parameters	Unit	LHS25	LHS50	LHS75	LHS100	LHS150	LHS200	LHS300	LHS400	LHS500	LHS600	LHS800	LHS1000	LHS1200	LHS1500
Nominal volume	L	25	50	75	100	150	200	300	400	500	600	800	1000	1200	1500
Feed quantity	L	10~20	20~40	30~60	40~80	60~120	80~160	120~240	160~320	200~400	240~480	320~640	400~800	480~960	600~1200
Impeller power	kW	2.2	4	5.5	11	15	18.5	22	30	37	45	55	55	75	75
Impeller speed	r/min	20~200	20~200	20~200	20~200	15~175	15~175	15~175	15~175	15~175	15~175	10~145	10~120	10~110	10~100
Granulation power	kW	1.1	2.2	3	4	3	5.5	7.5	7.5	11	11	15	15	18.5	2×18.5
Granulation speed	r/min	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000
Mill power	kW	0.75	0.75	0.75	1.1	3	3	3	4	4	5.5	5.5	5.5	5.5	2×5.5
Mill speed	r/min	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900
Air consumption	m³/min	0.4	0.4	0.4	0.4	0.6	0.6	0.6	0.6	1	1	1	1.5	1.5	2
Air pressure	MPa	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6

Featrures

Variety of Charging Methods: Vacuum charging/Lifter charging/Manual charging
Follow the regulations of cGMP, PIC/S GMP, FDA
Safety interlock system
Tangential impeller
On-line milling solution
WIP system

Advantages

Less material loss
Closed system (to discuss)
Easy cleaning
Granulation can be controlled by time, volume and power

Applications of High Shear Mixer in Pharmaceutical Manufacturing

The LHS Series high shear mixer is widely used in the following processes:

Wet granulation for tablet and capsule production — the most common application, producing uniform granules with controlled size distribution.
Powder mixing and homogenization — achieving uniform blends of active ingredients and excipients before granulation.
Effervescent tablet pre-mixing — handling moisture-sensitive formulations in a controlled environment.
Nutraceutical and food supplement manufacturing — processing dietary supplement powders and health food granules.
Chemical and battery material processing — granulating specialty powders for industrial applications.

FAQ

What is the capacity range of Canaan’s LHS high shear mixer?

The LHS Series covers 25L to 1500L bowl volume, suitable for lab-scale R&D through large-scale production.

How does the LHS high shear mixer achieve one-step granulation?

The LHS completes mixing, binder addition, and granulation in a single vessel. The impeller creates axial, radial, and tangential movement for uniform mixing, while the chopper cuts wet mass into granules — eliminating the need for separate mixing and granulating equipment.

What certifications does the LHS high shear mixer comply with?

The LHS Series complies with cGMP, PIC/S GMP, and FDA regulations. It features PLC program control, safety interlock systems, and WIP (wash-in-place) capability.

Learn More about the LHS Series High Shear Mixer

	Unit	LHS25	LHS50	LHS75	LHS100	LHS150	LHS200	LHS300	LHS400	LHS500	LHS600	LHS800	LHS1000	LHS1200	LHS1500
Nominal volume	L	25	50	75	100	150	200	300	400	500	600	800	1000	1200	1500
Feed quantity	L	10～20	20~40	30~60	40~80	60~120	80~160	120~240	160~320	200~400	240~480	320~640	400~800	480~960	600~1200
Impeller power	kW	2.2	4	5.5	11	15	18.5	22	30	37	45	55	55	75	75
Impeller speed	r/min	20~200	20~200	20~200	20~200	15~175	15~175	15~175	15~175	15~175	15~175	10~145	10~120	10~110	10~100
Granulation power	kW	1.1	2.2	3	4	3	5.5	7.5	7.5	11	11	15	15	18.5	2×18.5
Granulation speed	r/min	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000	1000~2000
Mill power	kW	0.75	0.75	0.75	1.1	3	3	3	4	4	5.5	5.5	5.5	5.5	2*5.5
Mill speed	r/min	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900	300~900
Air consumption	m3/min	0.4	0.4	0.4	0.4	0.6	0.6	0.6	0.6	1	1	1	1.5	1.5	2
Air pressure	MPa	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.6