--- title: Top 10 High-Containment Granulation Line Suppliers date: 2025-07-24T07:39:44Z modified: 2025-07-24T07:43:35Z permalink: "https://www.chinacanaan.com/blog/fluid-bed-granulation/high-containment-granulation-line-suppliers/" type: post status: publish excerpt: "" wpid: 4396 categories: - Fluid Bed Granulation featured_image: "https://www.chinacanaan.com/wp-content/uploads/2024/07/46ae2e5595e05d32c664.png" featured_image_alt: OEB5 High Containment Granulation Line Solution timestamp: 2025-07-24T07:43:35Z tags: - Fluid Bed Granulation --- The top 10 high-containment granulation line suppliers are **China Canaan**, **GEA Group**, **Glatt Group**, **Diosna**, **Nicomac**, **Avon Pharma Machines**, W**onsen, Schematic Engineering Industries**, **Senieer**, and **Tien Tuan Pharmaceutical**. The demand for manufacturing high-potency oral solid dosage (HP-OSD) pharmaceuticals is increasing, and it is predicted to grow to USD 15.32 billion in 2035 from USD 6.59 billion this year. As specialists in [pharmaceutical equipment solutions](https://www.chinacanaan.com/wp-content/uploads/wp-mfa-exports/post/what-equipment-does-a-pharmaceutical-lab-use.md), we understand the best granulation lines, especially as high containment for pharmaceuticals becomes more important due to the necessity for HP-OSD. In this article, we’ll highlight the top high-containment granulation line suppliers known for their innovation and performance. | **No.** | **Company Name** | **Website** | **Location** | | --- | --- | --- | --- | | 1 | Zhejiang Canaan Technology Limited | www.chinacanaan.com | Wenzhou, China | | 2 | Gea Group | www.cphi.com | Düsseldorf, Nordrhein-Westfalen | | 3 | Glatt Group | www.glatt.com | Binzen, Deutschland | | 4 | Diosna | www.diosna.com | Osnabrück, Germany | | 5 | Nicomac | nicomac.com | Milan, Italy | | 6 | Avon Pharma Machines | www.pharmaconex-exhibition.com | Vasai-Virar, India | | 7 | Wonsen (Yichun Wonsen Intelligent Equipment Co.) | www.wonsen.net | Yichun, China | | 8 | Schematic Engineering Industries | www.schematicind.com | Hyderabad, India | | 9 | Senieer | www.senieer.com | Chongqing, China | | 10 | Tien Tuan Pharmaceutical | tientuan.com.vn | Ho Chi Minh, Vietnam | ## **Zhejiang Canaan Technology Limited: Industry-Leading High Containment Solutions Supplier** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXcfuHVgz4ww60phw808VQJNuAGARNSsO6M4Ea4nFYE1ZbwewlwitV1tibU5toR6S7bhp2uVz4ZFZKwaq5iTd4QILuha2TVX3MQHkf_GFeVOQnBHKupJ-9HnTeO1_7t64CNy3WACWA?key=4MYF0TzytHXihTSgIWplqw) **Location:** Wenzhou, China **Founded Year:** 2000 **Canaan’s** was the first to be listed in the **A-share sector market** for solid dosage equipment, establishing it as a trusted global high containment granulation line supplier. Our **dedication to client satisfaction**, **significant R&D**, and an **expert team** enabled us to serve a wide range of sectors and address common difficulties. For example, cross-contamination is frequently a hazard when employing high-containment granulation lines since it could threaten people’s health because of unintentional mixing of drugs or chemicals. However, Canaan**’**s[ OEB5 High Containment Granulation Line Solution](https://www.chinacanaan.com/products/oeb5-high-containment-granulation-line-solution/) prevents this through its unique features to ensure fully closed material transfer systems, including - [Isolator](https://www.chinacanaan.com/products/isolator/) - AB valve - Automatic docking - Complying with GMP/CGMP/FDA regulations - And so on High-Performance Solutions from a Leading Pharma Machinery Manufacturer As a premier pharma machinery manufacturer, we deliver state-of-the-art wet granulation lines designed for maximum efficiency and regulatory compliance. Explore our advanced solutions to optimize your pharmaceutical production process. [View More Details](https://www.chinacanaan.com/wp-content/uploads/wp-mfa-exports/taxonomy/industry_cat/phrama.md) ![High-Performance Solutions from a Leading Pharma Machinery Manufacturer](https://www.chinacanaan.com/wp-content/uploads/2025/06/X-%E7%B3%BB%E5%88%97%E6%B9%BF%E6%B3%95%E5%88%B6%E7%B2%92%E7%BA%BF-RGB-e1749709429600.png) ## **Gea Group: Trusted OEB 5 Equipment Supplier** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXcD1VNi_E3p_jwxz89cb62rBp-M5CZm1MKtdu2gJ1hwaToWyFYepPyBPFuJRHnkCegbkAgLCBBqkcObYzYn_3d33ATuyN8jrWIjKnwUQkik7pKHxaJK-OkwbdvDI0ya0s7vDNp0WQ?key=4MYF0TzytHXihTSgIWplqw) **Location:** Düsseldorf, Nordrhein-Westfalen **Founded year:** 1881 One of the world’s largest high-containment granulation line suppliers, with operations in **150 countries** and expertise in machinery and process technologies. So, they produced enhanced high-containment granulation line products such as the **FlexStream 90**, which can handle **OEB 5 levels**. ## **Glatt Group: Robust High Containment Solutions** ## ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXeQDXVMpdKSrBcZOuyBIKyIck2YcEC6F9LyPBtp-TV_HWrEWQd1qWgq390KSpP3JjFoNTZqkjmwyPvo1vw_NFh-XjKAIMWJgam5uyZVAoqQlPAO83MJ0jPWbjoMH4kvRWqcvZ6llA?key=4MYF0TzytHXihTSgIWplqw) **Location:** Binzen, Deutschland **Founded Year:** 1954 They have more than **70 years of manufacturing experience** in many industries, including pharmaceuticals and feed. While they are well-known for their fluid bed systems, they are also a supplier of high containment granulation lines, providing integrated solutions with high quality and distinctive characteristics. This includes complete and tightly sealed systems that safeguard both the product and those who work with it. ## **Diosna: Flexible Granulation Line Under Isolator Options** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXfgoZ146_xeQ-FJd--C9y1j0Mj_pALZyso40F5BGu-I8bxz5AcUmlBLZVWnKNg0FKCGJm-D125TU_4GxYIw8P6nl1i-9ym9PXBAzGPmb5DgSN13EjrVoe0seZQIBVSL3mRQKx-_6w?key=4MYF0TzytHXihTSgIWplqw) **Location:** Osnabrück, Germany **Founded Year:** 1885 They have more than **140 years of experience** delivering advanced and efficient bakery sector’s dough mixing systems as well as pharmaceutical cutting-edge granulation and mixing technologies. Their **CSS granulation line series** contains automated and modern machines with multiple kinds of designs for their clients. They, like other high-containment granulation line suppliers, provide unique containment solutions in their product series meant for the safe handling of highly active pharmaceutical substances. ## **Nicomac: Supplier for AI-Enabled High Containment Solutions** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXfZEx8-OnSLBdTgUoeBAnM1Cx5SWv29QckBwJaRQY8XCnMvrbNr8E_BZqR7bfqsgd2VAqnSY4QrsG9L0ZK3KHtzfmw3GMI4C8obtxjAlBz20zpTYHxVWt6NAfTF6Rhm_2icBpT0WA?key=4MYF0TzytHXihTSgIWplqw) **Location:** Milan, Italy **Founded Year:** 1977 Nicomac is part of **Mangini Group**, which allows Mangini to offer a broader range of products, such as coating and granulation lines for pharmaceuticals and nutraceuticals. They also serve as high-containment granulation line suppliers who provide fully customized, turnkey granulation lines with particular features like **PLC** and **an Artificial Intelligence Platform.** ## **Avon Pharma Machines: Scalable and Secure Potent Compound Handling Granulation Line** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXczAcc7OvRrBkG_qsZC1XghEttgEgIcMl1seIiNxQmJSaqvx5gR4_0WcYl-Jdp_2s0HSTT1f4LHsMsK5-d87ZSwTjUwLWC2bCmXuti1dgFu9oOAUGbV4DNn3RGpeBm5S6UHVVhb4w?key=4MYF0TzytHXihTSgIWplqw) **Location:** Vasai-Virar, India **Founded Year:** 1986 One of the high-containment granulation line suppliers that stands out from their wide product line for pharmaceutical formulation, bulk medication, and API businesses, including tableting. Their **Integrated Granulation Suite (IGS)** can handle a variety of production sizes and has special qualities, such as a short drying time while giving full protection to workers from harmful and toxic materials. ## **Wonsen (Yichun Wanshen Pharmaceutical Machinery): Tailored High Containment Granulation Line Supplier** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXcDdF0Qt5ije6VJ3JjEscDlWx_APCR-kcsC-t5xk21uw5A-rT-MAeMFgH7XP0PdI7ajyrrKq9s-sNq9Ba0_F98gbQfnfCyM_q_JWfmJ_RWbOGoneZEzTeokvV0x_VaYk2Gd_7S4eg?key=4MYF0TzytHXihTSgIWplqw) **Location:** Yichun, China **Founded Year:** 2010 Wonsen also had high expertise in intelligent information systems and pharmaceutical equipment, with exports in **30** countries and regions. Hence, they are among the high-containment granulation line suppliers globally, producing specialized, high-quality pharmaceutical process products, including a **high-containment wet-type granulation line** capable of handling **OEB 4 levels.** ## **Schematic Engineering Industries: Cutting-Edge OEB 5 Equipment Designs** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXdl6KrG8CTxcNb2wePdM_3hlI3BNrVJ4MhWjx4hSc0TGynTkI33fPWKsD1LXufjmN-s1faz0GjQbt1yuotEo9WAwl2x1Ou_PZY671wuOOHwwQLNfqQTQSLoHWf9cFiHwxi_TDJEYw?key=4MYF0TzytHXihTSgIWplqw) **Location:** Hyderabad, India **Founded Year:** 2012 One of the high-containment granulation line suppliers also devotes itself to manufacturing cutting-edge products in order to serve their customers with superior service. Being a specialist in containment and barrier isolator equipment, they supplied a versatile **wet and dry granulator line with isolators** capable of handling both **OEB4 and OEB5 levels**. ## **Senieer: Turnkey Potent Compound Handling Lines Supplier** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXeaUr10dEMTDJzJ0elhFg-SLBTYoRFDVLxe8C0j7ZKDMxP0hMS9p9xa06A7mZGBvNNuGxHgQagtFmEs_pgy467hh4DRqrLEgUCCA5Km9xTTIc1mmNfZVZiVDC-5ZdpE9_K18inPvw?key=4MYF0TzytHXihTSgIWplqw) **Location:** Chongqing, China **Founded Year:** 1998 They’re also high-containment granulation line suppliers that offer turnkey projects or full-process services with expertise in solid dosage forms, powder, and much more. They provided configurable, scalable, and energy-efficient high-containment granulation lines for the pharmaceutical, food, and chemical industries. ## **Tien Tuan Pharmaceutical: Advanced and Wall-Mounted Granulation Line Suppliers** ![](https://lh7-rt.googleusercontent.com/docsz/AD_4nXfZwsGLhQa_ZxCVJBLS5lawMh_7NEjd_S4iiutEmyQFeYE3yqi49WKykQjOceFobLXxUzilfb35MUw8TUg4XPO7k_w82cLTJGmCJE-6nX-mqAQatEDzuB6Vaf5XzmrigWVLCg3GCA?key=4MYF0TzytHXihTSgIWplqw) **Location:** Ho Chi Minh, Vietnam **Founded Year:** 1990 They’re also a global company with a specialty in processing and packaging oral solid dosage machinery for the oral dosage form industries. Hence, they’re one of the high-containment granulation line suppliers who produce highly inventive and tailored granulation lines with isolators that meet **OEB 4 and 5** specifications. They include additional specific components, such as **split butterfly valves** and **wall-mounted designs**, to improve the machine’s reliability. ## **Main Takeaways: High-Containment Granulation Line Suppliers** Each of the high-containment granulation line suppliers delivers a unique specialty, allowing them to prioritize both pharmaceutical worker safety and product reliability. Therefore, **China Canaan**, **Gea Group**, **Glatt Group**, **Diosna**, **Nicomac**, **Avon Pharma Machines**, **Wonsen**, **Schematic Engineering Industries**, **Senieer**, and **Tien Tuan Pharmaceutical** are the leading suppliers in this industry. [**Canaan**](http://canan)**‘s** team members specialize in designing and providing advanced granulation solutions that are specifically tailored to your protection and performance needs. [**Contact us today**](https://www.chinacanaan.com/wp-content/uploads/wp-mfa-exports/page/contact.md) for more product information and to begin working with one of the most reliable high-containment granulation line suppliers!