---
title: Pharmaceutical Granulation Solutions – High-Performance Pharmaceutical Granulation Machines
date: 2025-06-07T02:52:33Z
modified: 2026-08-07T02:16:41Z
permalink: "https://www.chinacanaan.com/pharmaceutical-granulation-machines/"
type: page
status: publish
excerpt: ""
wpid: 3851
timestamp: 2026-08-07T02:16:41Z
tags: []
---
High-Performance Pharmaceutical Granulation Machines
# Pharmaceutical Granulation Solution
Canaan Technology specializes in pharmaceutical granulation equipment and technologies that transform fine powders into high-quality granules—ideal for the production of tablets, capsules, and other solid dosage forms. Our granulation process meets the highest standards of efficiency, consistency, and regulatory compliance.
[ Get a Quote
](#1)
[ Explore Our Solutions
](#2)
## What is Granulation in Pharmaceutical Industry?
Granulation in the pharmaceutical industry is the process of converting fine powders into cohesive granules, improving **flowability**, **compressibility**, and **content uniformity**. This step is crucial for consistent tablet quality and dosage accuracy.
- Improve Flowability
The granulation process makes powder particles more uniform, improving their flow through production equipment and reducing clogging and inconsistencies.
- Enhance Compressibility
Granulation gives powder particles better compression properties, allowing the formation of tablets with moderate strength and smooth surfaces.
- Ensure Uniformity
Granulation helps ensure the drug ingredients are evenly distributed in the final product, improving dosage accuracy and product quality consistency.
######
## Types of Granulation in Pharmaceutical Industry
- Wet Granulation
Producing dense, controlled-release particles with high drug solubility. A binder solution is added to form a moist mass, followed by drying and sizing.
#### Features:
- Less material and energy loss
- WIP/CIP
- Closed system
- Comply 21CFR Part 11 requirement
- Comply GMP/FDA requirement, CE certified
#### Capacity:
- From 1L (Lab) to 1500L (Production)
- Scale up
- Changeable Bowl
[  ](https://chinacanaan.com/products/lhss-series-laboratory-high-shear-mixer/#pmain)
##### [Lab High Shear Mixer >>](https://chinacanaan.com/products/lhss-series-laboratory-high-shear-mixer/#pmain)
[  ](https://chinacanaan.com/products/high-shear-mixer-with-mill/#pmain)
##### [High Shear Mixer >>](https://chinacanaan.com/products/high-shear-mixer-with-mill/#pmain)
[  ](https://chinacanaan.com/products/lgx-series-laboratory-roller-compactor/#pmain)
##### [Lab Roller Compactor >>](https://chinacanaan.com/products/lgx-series-laboratory-roller-compactor/#pmain)
[  ](https://chinacanaan.com/products/lgx-series-roller-compactor/#pmain)
##### [Roller Compactor >>](https://chinacanaan.com/products/lgx-series-roller-compactor/#pmain)
- Dry Granulation
Dry granulation is ideal for processing heat-sensitive or moisture-absorbing materials.
#### Features:
- Less material and energy loss
- WIP/CIP
- Closed system, dust free
- Comply 21CFR Part 11 requirement
- Comply GMP/FDA requirement, CE certified
#### Capacity:
- From 0.1kg/h-700kg/h
- Scale up
- Dry Granulation
Dry granulation is ideal for processing heat-sensitive or moisture-absorbing materials.
#### Features:
- Less material and energy loss
- WIP/CIP
- Closed system, dust free
- Comply 21CFR Part 11 requirement
- Comply GMP/FDA requirement, CE certified
#### Capacity:
- From 0.1kg/h-700kg/h
- Scale up
[  ](https://chinacanaan.com/products/lgx-series-roller-compactor/#pmain)
##### [Roller Compactor >>](https://chinacanaan.com/products/lgx-series-roller-compactor/#pmain)
[  ](https://chinacanaan.com/products/lgx-series-laboratory-roller-compactor/#pmain)
##### [Lab Roller Compactor >>](https://chinacanaan.com/products/lgx-series-laboratory-roller-compactor/#pmain)
- One-step Granulation (Boiling Granulation)
Integrated drying, granulation, and coating, it reduces labor works and control cross-contamination.
#### Features:
- Ex-proof (ATEX certified), more safety
- WIP/CIP
- Wall-mounted design, space saving
- Comply 21CFR Part 11 requirement
- Comply GMP/FDA requirement, CE certified
#### Capacity:
- From 0.5kg/batch-500kg/batch
(top spray)
- Scale up
[  ](https://chinacanaan.com/products/fzs-series-laboratory-fluid-bed-multi-processor/#pmain)
##### [Lab Fluid Bed Processor >>](https://chinacanaan.com/products/fzs-series-laboratory-fluid-bed-multi-processor/#pmain)
[  ](https://chinacanaan.com/products/fz-series-fluid-bed/#pmain)
##### [Fluid Bed Processor >>](https://chinacanaan.com/products/fz-series-fluid-bed/#pmain)
## Canaan Wet Granulation Line for Pharmaceutical Industry
Canaan **X Series** Wet Granulation Line is a high-containment, automated pharmaceutical production system. It includes multiple interconnected processing units for wet granulation, typically used in the production of solid oral dosage forms like tablets and capsules.
### The Granulation Line is integrated with:
- High Shear Mixer (HSM) – for wet granulation
- Fluid-Bed Processor – for drying and possible coating
- Dry Milling Machine – for milling
- Coater – for coating
- Operation Interface – for process automation and control
### Features:
- High efficiency
- Ex-proof
- Clean-in-place (CIP) or wash-in-place (WIP)
- High safety and containment (up to OEB5)
- Comply 21CFR Part 11 requirement
- Comply GMP/FDA requirement, CE certified
[ Explore More Details
](https://chinacanaan.com/products/x-series-wet-granulation-line/#pmain)
Contact Canaan
Request a Tailored Pharmaceutical Granulation Solution for Your Project
Benefits you can get from Canaan:
- Custom granulation machine for your pharmaceutical granulation project
- Advanced granulation solutions
- Full-process granulation technology consulting
- Fully meets GMP, FDA, CE standards
**Email:** canaan@chinacanaan.com**Telepon:** +86-577-67378828
## Canaan – Your Trusted Pharmaceutical Granulation Machine Manufacturer
Canaan brings over 20 years of experience in delivering turnkey solutions for pharmaceutical granulation systems. From equipment selection to system integration and regulatory compliance, we provide complete, worry-free granulation solutions tailored to your production needs.
https://www.youtube.com/watch?v=G0nGsUh5WcE&t=3s
Founded in 2000 and headquartered in Wenzhou, China, Zhejiang Canaan Technology Limited is a **global leader in pharmaceutical equipment manufacturing**.
With over 1,700 customers across Germany, Italy, Japan, Korea, and beyond, we deliver advanced, high-performance solutions for pharmaceutical solid dosage production.
**Our granulation systems are at the core of fully integrated OSD (Oral Solid Dosage) lines—engineered for efficiency, uniformity, and full regulatory compliance.**
We proudly support global pharma leaders like Sanofi, GSK, Pfizer, MSD, Merk, Abbott, Bayer, Bosch etc. with reliable, innovative solutions.
[ Tell Us Your Project
](#1)
## Why Choose Canaan Technology
### Canaan Your Trusted Partner:
- Over 20 years of industry experience
- Global clients including Sanofi, GSK, Pfizer, Abbott, etc.
- CE/ISO-certified and GMP/FDA-compliant machines
- Complete granulation lines and turnkey solutions
### Solutions Include:
- Concept Design
- After-sales and Maintenance
- On site Commissioning
- Compliance Validation
- Engineering Project Management
## Get Your Pharmaceutical Granulation Solution Right Now!
[ Get A Quote
](#1)
## Meet Us at Industry Trade Shows
As a regular participant in leading global pharmaceutical and processing exhibitions, we warmly invite our partners and clients to visit us. We will be exhibiting at **CPHI China (June 24–26, 2025, Shanghai, China) and CPHI Frankfurt （28-30 October, 2025, Frankfurt, Germany)**.
At these events, we will spotlight our high-performance wet granulation machines, designed to deliver exceptional efficiency, uniformity, and regulatory compliance in solid dosage production. Come explore our latest innovations and discuss tailored solutions for your pharmaceutical manufacturing needs.
## Frequently Asked Questions
Table of Contents
### What’s the Difference Between Wet and Dry Granulation?
| Aspect | Wet Granulation | Dry Granulation |
| --- | --- | --- |
| Binder Use | Requires a liquid binder | No binder or liquid needed |
| Moisture Sensitivity | Not ideal for moisture-sensitive materials | Ideal for moisture- and heat-sensitive materials |
| Granule Strength | Produces dense, strong granules | Strength varies with compaction |
| Dust Generation | Minimal due to moisture | Higher dust during processing |
| Processing Time | Longer, includes drying step | Faster, no drying needed |
| Applications | Tablets, capsules, sprinkle granules | Friable powders, moisture/heat-sensitive formulations |
### How Does the Granulation Process Work?
1. **Mixing**: Active ingredients and excipients are combined.
2. **Granulation**: The mixture is agglomerated via wet or dry methods.
3. **Drying**: (Only in wet granulation) The granules are dried to the desired moisture level.
4. **Sizing**: Granules are screened to ensure uniform particle size.
Our **granulation process in pharmaceutical industry** meets the strictest global **pharma granulation guidelines**.
### Why is Granulation Important in Pharma?
Granulation plays a key role in pharmaceutical manufacturing, as it improves **tablet granulation**, ensures **content uniformity**, and enhances **compressibility** and **flowability** in solid dosage forms like tablets and capsules. It’s essential for ensuring consistent drug release and quality control.
| Aspect | Wet Granulation | Dry Granulation |
| --- | --- | --- |
| Binder Use | Requires a liquid binder | No binder or liquid needed |
| Moisture Sensitivity | Not ideal for moisture-sensitive materials | Ideal for moisture- and heat-sensitive materials |
| Granule Strength | Produces dense, strong granules | Strength varies with compaction |
| Dust Generation | Minimal due to moisture | Higher dust during processing |
| Processing Time | Longer, includes drying step | Faster, no drying needed |
| Applications | Tablets, capsules, sprinkle granules | Friable powders, moisture/heat-sensitive formulations |
1. **Mixing**: Active ingredients and excipients are combined.
2. **Granulation**: The mixture is agglomerated via wet or dry methods.
3. **Drying**: (Only in wet granulation) The granules are dried to the desired moisture level.
4. **Sizing**: Granules are screened to ensure uniform particle size.
Our **granulation process in pharmaceutical industry** meets the strictest global **pharma granulation guidelines**.
Granulation plays a key role in pharmaceutical manufacturing, as it improves **tablet granulation**, ensures **content uniformity**, and enhances **compressibility** and **flowability** in solid dosage forms like tablets and capsules. It’s essential for ensuring consistent drug release and quality control.