--- title: "No More Sticking: Fluid Bed Tech Revolutionizes Effervescent Tablets" date: 2025-07-03T05:38:19Z modified: 2025-07-03T06:09:34Z permalink: "https://www.chinacanaan.com/product-innovation/no-more-sticking-fluid-bed-tech-revolutionizes-effervescent-tablets/" type: post status: publish excerpt: "" wpid: 4308 categories: - Fluid Bed Granulation - Products - Technology featured_image: "https://www.chinacanaan.com/wp-content/uploads/2025/07/1a1cc30a-f3da-43c7-9ce0-8eab26ebbaf0.png" timestamp: 2025-07-03T06:09:34Z tags: - Fluid Bed Granulation - Products - Technology --- Customer review: “A problem that lasted three years—Canaan solved it in just two months!” “The Canaan team not only provides equipment, but also empowers the entire process from formulation optimization to process validation. Their fluid bed technology has transformed our effervescent tablet production line, with zero viscosity and impact in the tablet pressing process, doubling production capacity and achieving the best quality stability in history! ——The production manager of the pharmaceutical company ![](https://www.chinacanaan.com/wp-content/uploads/2025/07/1a1cc30a-f3da-43c7-9ce0-8eab26ebbaf0-1.png) In the pharmaceutical industry, the advancement of process technology often significantly improves production efficiency. For a pharmaceutical company, **the long-standing problem of “tablet sticking and astringency” in the production of effervescent tablets is a major obstacle** to improving quality and efficiency. Although the traditional high shear wet granulation process is widely used, its disadvantages such as long granulation time, poor particle uniformity, and insufficient process stability result in frequent shutdowns and high waste tablet rates in the tablet pressing process, and even affect the stability of drug quality. A customer in Beijing has been struggling with technology for three years without success, and multiple domestic equipment technology manufacturers have also failed to provide effective solutions. ### Limitations of Traditional Craftsmanship ▼ The effervescent tablets have extremely strict requirements for particle quality. Although traditional high shear wet granulation can quickly mix, it has obvious shortcomings: long drying time (5-6 hours) and uneven distribution of particle moisture. These issues lead to increased friction between the particles and the mold during tablet pressing, resulting in adhesive impact and edge collision. At the same time, the low precision of process parameter control and large differences between batches further amplify production volatility. The main pressure in the tablet pressing process is as high as 35KN, with high operating noise and limited speed (only 66000 tablets/hour), which not only consumes high energy but also becomes a key bottleneck restricting production capacity. ### The Way to Break Through: Innovation of Fluid Bed Technology ▼ Canaan Technology, based on in-depth analysis of customer product characteristics, breaks through traditional thinking and proposes an innovative process solution of “fluid bed one-step granulation+tablet pressing”, and optimizes the prescription process. This plan achieves a qualitative leap through three core advantages: #### 01 Precise control to enhance process stability: The fluid bed process uses **an intelligent parameter control system to accurately regulate key parameters such as inlet air temperature, air speed, and atomization pressure**, ensuring the uniformity of particle drying. The unique air volume distribution design ensures consistent particle movement trajectory and **a moisture distribution difference of ≤ 0.5%**, eliminating the risk of adhesive flushing caused by local excessive humidity from the source. ![](https://www.chinacanaan.com/wp-content/uploads/2025/07/企业微信截图_17515057061128.png) ![](https://www.chinacanaan.com/wp-content/uploads/2025/07/企业微信截图_17515060328563.png) #### 02 Particle homogenization, optimizing tablet performance: One step granulation in fluid bed significantly reduces the granulation drying time to **1 hour**, resulting in a narrow particle size distribution **(D50 controlled between 150-250 μm)** and significantly improved flowability. Compared to traditional techniques, the amount of fine powder particles is **reduced by 30%**, and the contact between the mold and particles is more uniform during tablet pressing. The main pressure dropped sharply from 35KN to 8KN, reducing equipment loss by 60%, increasing the **tablet pressing speed to 100000-120000 tablets/hour**, and running smoothly without vibration. ![](https://www.chinacanaan.com/wp-content/uploads/2025/07/d0998b32-2cf0-4e59-a593-4f22e89175e6-768x1024.jpg) ![](https://www.chinacanaan.com/wp-content/uploads/2025/07/1f8b84f8-e4b8-4044-aeac-b7ed5d86c03c-768x1024.jpg) #### 03 Whole process quality control significantly reduces waste rate: The durability verification of the process shows that **the key quality indicators (bulk density, moisture, particle size) of six consecutive batches of particles have remained stable within the qualified range. The waste tablet rate has significantly decreased from 1-2kg/batch to 200-500g/batch, with an 80% increase in production efficiency and an annual cost savings of over one million yuan.** | Index | Original Process | Innovative New Technology | | --- | --- | --- | | Granulation Drying Time | 5-6h | 1h | | Tableting Speed | 66000/h | 100000-120000/h | | Main Pressure | 35KN | 8KN | | Waste Tablets Quantity | 1-2kg/Batch | 200-500g/Batch | | Process Stability | There are sticky and rough flushing phenomena in batches, and occasionally unqualified batches | All 6 batches have no sticking or astringency, and are 100% qualified | ### Smart Canaan: Driving the Future of the Industry with Technological Innovation ▼ In the era of pharmaceutical industry 4.0, Canaan Technology adheres to the concept of “winning by quality”, deeply integrating fluid bed one-step granulation technology with AIoT intelligent monitoring system to achieve real-time optimization of process parameters, fault warning and data traceability. **From “solving single problems” to “building process standards”, we are committed to providing pharmaceutical companies with full lifecycle process solutions, helping customers find the optimal balance between compliance, efficiency, and cost.** **Cracking the sticking dilemma of effervescent tablets is a typical case of Canaan Technology empowering the pharmaceutical industry.** In the future, we will continue to use innovation as the engine and quality as the cornerstone, working together with pharmaceutical companies to move towards a new era of “intelligence, efficiency, and zero defects”. Let every pill carry the ingenuity and commitment of intelligent craftsmanship. **Smart Canaan makes pharmaceuticals simpler!** ![Animated GIF](https://www.chinacanaan.com/wp-content/uploads/2025/06/230d0b01-c672-452d-98b3-7800096c31e3.gif)