The traditional process in the production of API is: crystallization tank for crystallization → centrifuge for solid-liquid separation → clean the crystal with detergent → solid-liquid separation → manual discharge → loaded into trays → double-cone (or vacuum drying oven) drying → manual discharge → loaded into raw material barrels, which cannot meet the requirements of GMP.
FWDF Series Agitated Nutsche Filter Dryer is an equipment that integrates the processes of filtration, washing and drying. Its airtight, high in automation, easy to operate, high in recycling efficiency, and completion in safety measures, which greatly reduces the labor force of workers. This product also has the following features:
◎ The production system process can completely realize the fully closed production process from the feed of the crystalline solid-liquid suspension to the auto discharge of the raw material after drying, with solid-liquid mixing function, filter cake cleaning function, filtration and dehydration function, discharge dryer function, CIP/SIP function, in line with the requirements of GMP.
◎ Since the production is carried out under the fully closed condition, the hydraulic motor discharge valve structure is driven by the lead screw, which can still maintain the overall sealing of the FWDF even when the pressure of the hydraulic station is lost.
◎The chassis has a multi-channel sealing structure and leakage observation device with a collection function, which can detect safety accidents caused by chassis leakage on time, reduce the occurrence of personnel poisoning and allergy accidents caused by contact with toxic products, and it meets EHS requirements.
◎In the CIP (clean-in-place) process, organic solvents and process water are used to clean the filter cake and tank without disassembling the equipment, reducing the risk of contamination and cross-contamination to a low level, so that ensuring the material and man-machine safety.
◎ The discharge valve is designed with a special spray and purge device, which can purge and clean the spool and seal seat without removing the valve body of the discharge valve, effectively prevent cross contamination and better protect the product; In addition, the volatile amount of organic solvent used in production is very small, which can be nearly 100% recovery, with great economic benefits.
◎Techpro-M control system is adopted, which has the functions of parameter setting, historical trend, formula setting, batch report and so on. It provides rich data information for the production process, and also provides powerful support for the factory information production.
Canaan will continue to improve the production efficiency of API refining, improve drug quality and production environment to provide new technology, welcome every pharmaceutical enterprise to test.